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Here's What's New—and Still on the Horizon—on Harlem's Rapidly-Transforming 125th Street



A wave of new buildings and businesses continues to transform Harlem's 125th Street.


Glossy high-rises, like the 28-story Renaissance New York Harlem Hotel that opened in the summer of 2023, have already significantly altered the skyline.


Major retailers that arrived this year, including Trader Joe's, Sephora and Target, are behind the jaw-dropping changes at street level.


To track the latest shifts, TCU has taken a walk down the iconic thoroughfare between Fifth Avenue and Broadway.

Here are the most notable recent openings, plus what's still on the horizon, from east to west:


2033 Fifth Ave at 125th St

Theater opening: TBA

This massive 21-story residential, commercial, and cultural development is set to be the new home of the National Black Theatre, founded in 1968 at the same address. The building had its topping-out ceremony in October 2023.


5 W 125th St between Fifth and Lenox Aves

Opened: October 2024

This new food delivery concept with more than a dozen locations in NYC allows customers to order from a variety of restaurants run by top chefs, including Bobby Flay (Bobby Flay Steak) and Harlem's own Marcus Samuelsson (Streetbird).


17 W 125th St between Fifth and Lenox Aves

Opened: March 2024

The Cajun-style seafood boil chain now has a location on 125th Street.


PB Brasserie at 60 W 125th Street.

60 W 125th St between Fifth and Lenox Aves

Opened: August 2024

This 4,500-square-foot restaurant from the team behind Ponty Bistro and Renaissance Harlem is serving up seafood (Chilean sea bass with garlic spinach) and steak (dry age New York strip) on the ground floor of a modern development just east of Lenox Avenue.


66 W 125th St between Fifth and Lenox Aves

Opened: March 2024

The Guatemalan chain is known for its signature fried chicken served with sides like yuca fries and beans.


100 W 125th St between Lenox Ave and Adam Clayton Powell Jr. Blvd

Opened: November 2023

The fast fashion chain shut the doors to its old location at 125 W 125th Street in August 2023, reopening a few months later across the street, right next to the Whole Foods.


Signs on the facade of the Trader Joe's Harlem on 125th Street.
Trader Joe's and Target are both now open at 121-123 W 125th Street.

121 W 125th St between Lenox Ave and Adam Clayton Powell Jr. Blvd

Openings: Sephora and Trader Joe's opened in July 2024, Target opened in October 2024

Long in the works, the glossy future home of the National Urban League welcomed a long list of major retailers this summer, including Trader Joe's, Target, and Sephora. The Urban Civil Rights Museum is looking to open in the same building sometime in 2025-2026.


124 W 125th St between Lenox Ave and Adam Clayton Powell Jr. Blvd

The fast-growing chain, originally from Louisiana, is known for its simplified menu focused on chicken fingers, signature Cane's sauce, Texas toast, and crinkle fries.


130 W 125th St between Lenox Ave and Adam Clayton Powell Jr. Blvd

Opened: winter 2024

The ubiquitous Chinese food spot recently opened in a single-story building that was once a Burger King.


144 W 125th St between Lenox Ave and Adam Clayton Powell Jr. Blvd

Opening: Fall 2025

The Studio Museum in Harlem recently announced that its modern new home, designed by architect David Adjaye, will open in the fall of 2025.



222 W 125th St between Adam Clayton Powell Jr. and Frederick Douglass Blvd.

The British sneaker and sportswear chain recently joined other newcomers like Nike and Snipes on 125th Street.


233 W 125th St between Adam Clayton Powell Jr. and Frederick Douglass Blvds

Opened: August 2023

Decorated with Harlem Renaissance-themed touches, this new 211-room hotel owned by Marriot includes a restaurant and piano bar on the fifth-floor lobby.


What's Recently Opened—and Still on the Horizon—on Harlem's Rapidly-Trasforming 125th Street
The Renaissance New York Harlem Hotel sits above the new Apollo Stages at the Victoria Theater.

233 W 125th St between Adam Clayton Powell Jr. and Frederick Douglass Blvds

Opened: February 2024

Two new flexible performance spaces run by the legendary Apollo Theater are now open in the historic Thomas Lamb-designed Victoria Theater directly under the Renaissance New York Harlem Hotel.


248 W 125th St between Adam Clayton Powell Jr. and Frederick Douglass Blvds

Opened: October 2023

Harlem's first licensed cannabis shop, which most of you greeted with open arms, is now doing business directly across the street from the Apollo.


Gotham Buds is Harlem's first licensed cannabis shop.

254 W 125th St between Adam Clayton Powell Jr. and Frederick Douglass Blvds

Opened: March 2024

This rapidly-expanding Nashville-style hot chicken chain—investors include Drake and Samuel L. Jackson—is just down the block from the Chick-fil-A that opened last year.


321 W 125th St and St. Nicholas Ave

Opening: November

The fast-casual Mexican chain is set to open in the old Popeyes space (the fried chicken spot is reopening just a few doors down the block).


362 W 125th St between St. Nicholas and Morningside Aves

Opening: TBA

This New Jersey-based gym will be opening in the sleek 12-story condo known as Eleven Hancock.


600 W 125th St and Broadway

Estimated construction completion: 2024

Columbia University's new 34-story building will house graduate students and faculty once it's finished. McDonald's is returning to the ground level.


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